pineal gland – mass constant in a growing organism
The pineal gland is the only gland in the body, the size of which remains constant throughout almost the entire life of a person. To be precise, the volume of the gland increases up to 2 years, and then the growth stops and remains constant until the end of life, and also hardly differs in people depending on gender, height and body weight. That is, the volume of the pineal gland is a kind of constant for a relatively rapidly growing child’s body and the general diversity of mankind.Consequently, as the body grows, the ratio of pineal gland mass to body mass by the age of 25 decreases almost 10 times, and this, in turn, should lead to a proportional decrease in the level of melatonin, which simply dissolves in the growing volume of tissues.
Large deviations from the mean may be due to differences in body fat. For example, in a study of children with overweight and obesity, there was an accelerated onset of puberty. These results can be explained by the high solubility of melatonin in lipids (adipose tissue) and low solubility in water (muscle tissue). Thus, the key role in the timing of puberty is most likely not body weight, but the volume of adipose tissue. True, the critical value for this parameter has not yet been determined.
Another example of the validity of the hypothesis discussed here is dwarfism, in which the size of the pineal gland corresponds to that of a healthy person with less body weight. For example, with Laron’s dwarfism, puberty is delayed until the obesity characteristic of these patients increases the volume of adipose tissue to a critical value.Поділитися цим: